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**Selected for 2026 Doody's Core Titles in Hematology/Oncology** Extensively revised, comprehensive content from leading global contributors ensures that Hematology, 8th Edition, remains your #1 choice for expert guidance in all areas of this rapidly advancing subspecialty. This edition reflects the numerous advances that are redefining the field and dramatically influencing new approaches to diagnosis, treatment, and outcomes. Well-illustrated and clinically focused, it details the basic science and clinical practice of hematology and hematopoietic cellular therapy-covering virtually all aspects of hematology in one definitive resource. Covers all hematologic disorders, including comprehensive discussions of hematologic malignancies, individualized patient care, cell-based therapies, transplantation, transfusion medicine, hemostasis, thrombosis, and consultative hematology-in one convenient volume Provides state-of-the-art guidance from global experts at the forefront of the latest research and clinical practice Provides extensive updates throughout on basic science research, advances in molecular diagnostics, new drugs, immunotherapies, personalized medicine, laboratory medicine, transfusion medicine, stem cell transplantation, and clinical treatment for all hematologic malignancies and non-malignancies Contains new chapters on gene editing; the impact of mitochondria on hematopoiesis; myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes; immunotherapy and management of its toxicities; transfusion medicine in sickle cell disease; principles of radiation therapy; and COVID-19, including complications of vaccination and its impact on the hematologic system Discusses many new advances in the field, including details and the future of gene therapy for hemophilia, gene editing for sickle cell disease and thalassemia, the evolution of cellular therapy, use of cells, transfusion medicine vs. protein therapy, gene sequencing, immunotherapy, and new targeted drugs Includes more decision-making algorithms for formulating diagnoses and personalized treatment plans for those highly complex disorders that require individualized approaches Addresses the effects of aging on hematopoiesis and on the manifestations of a variety of hematologic disorders Discusses cardio-oncology and its impact on the treatment of patients with hematologic disorders Presents relevant basic science as background for clinical application in later sections An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

This edition is heavily outdated and we have a new edition with PyTorch examples published! Key Features: - Code examples are in TensorFlow 2, which make it easy for PyTorch users to follow along - Look inside the most famous deep generative models, from GPT to MuseGAN - Learn to build and adapt your own models in TensorFlow 2.x - Explore exciting, cutting-edge use cases for deep generative AI Book Description: Machines are excelling at creative human skills such as painting, writing, and composing music. Could you be more creative than generative AI? In this book, you'll explore the evolution of generative models, from restricted Boltzmann machines and deep belief networks to VAEs and GANs. You'll learn how to implement models yourself in TensorFlow and get to grips with the latest research on deep neural networks. There's been an explosion in potential use cases for generative models. You'll look at Open AI's news generator, deepfakes, and training deep learning agents to navigate a simulated environment. Recreate the code that's under the hood and uncover surprising links between text, image, and music generation. What You Will Learn: - Export the code from GitHub into Google Colab to see how everything works for yourself - Compose music using LSTM models, simple GANs, and MuseGAN - Create deepfakes using facial landmarks, autoencoders, and pix2pix GAN - Learn how attention and transformers have changed NLP - Build several text generation pipelines based on LSTMs, BERT, and GPT-2 - Implement paired and unpaired style transfer with networks like StyleGAN - Discover emerging applications of generative AI like folding proteins and creating videos from images Who this book is for: This is a book for Python programmers who are keen to create and have some fun using generative models. To make the most out of this book, you should have a basic familiarity with math and statistics for machine learning. Table of Contents - An Introduction to Generative AI: "Drawing" Data from Models - Setting up a TensorFlow Lab - Building Blocks of Deep Neural Networks - Teaching Networks to Generate Digits - Painting Pictures with Neural Networks using VAEs - Image Generation with GANs - Style Transfer with GANs - DeepFakes with GANs - The Rise of Methods for Text Generation - NLP 2.0: Using Transformers to Generate Text - Composing Music with Generative Models - Play Video Games with Generative AI: GAIL - Emerging Applications in Generative AI

Examining the enormous potential of microbiome manipulation to improve health   Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease.   In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: * How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. * The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. * The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. * Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes.   Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

**Selected for 2026 Doody's Core Titles in Hematology/Oncology** Extensively revised, comprehensive content from leading global contributors ensures that Hematology, 8th Edition, remains your #1 choice for expert guidance in all areas of this rapidly advancing subspecialty. This edition reflects the numerous advances that are redefining the field and dramatically influencing new approaches to diagnosis, treatment, and outcomes. Well-illustrated and clinically focused, it details the basic science and clinical practice of hematology and hematopoietic cellular therapy-covering virtually all aspects of hematology in one definitive resource. Covers all hematologic disorders, including comprehensive discussions of hematologic malignancies, individualized patient care, cell-based therapies, transplantation, transfusion medicine, hemostasis, thrombosis, and consultative hematology-in one convenient volume Provides state-of-the-art guidance from global experts at the forefront of the latest research and clinical practice Provides extensive updates throughout on basic science research, advances in molecular diagnostics, new drugs, immunotherapies, personalized medicine, laboratory medicine, transfusion medicine, stem cell transplantation, and clinical treatment for all hematologic malignancies and non-malignancies Contains new chapters on gene editing; the impact of mitochondria on hematopoiesis; myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes; immunotherapy and management of its toxicities; transfusion medicine in sickle cell disease; principles of radiation therapy; and COVID-19, including complications of vaccination and its impact on the hematologic system Discusses many new advances in the field, including details and the future of gene therapy for hemophilia, gene editing for sickle cell disease and thalassemia, the evolution of cellular therapy, use of cells, transfusion medicine vs. protein therapy, gene sequencing, immunotherapy, and new targeted drugs Includes more decision-making algorithms for formulating diagnoses and personalized treatment plans for those highly complex disorders that require individualized approaches Addresses the effects of aging on hematopoiesis and on the manifestations of a variety of hematologic disorders Discusses cardio-oncology and its impact on the treatment of patients with hematologic disorders Presents relevant basic science as background for clinical application in later sections An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud